Thursday 25 April
Claire Steves is a clinically active geriatrician at Guys and St Thomas’s NHS Foundation Trust, and a Senior Clinical Lecturer at King’s College London. She has an active portfolio of research into early predictors of frailty and conditions of ageing. She is Deputy Director (Clinical) for the Department of Twin Research and Genetic Epidemiology, which is home to the TwinsUK cohort – one of the most deeply phenotyped and genotyped twin cohorts in the world. The cohort has an average age of 65, and Claire leads the characterization of physical and mental ageing traits and frailty in the cohort, including recently characterization of oral health. Her particular research focus is the relationship between the gut, urinary and salivary microbiome and conditions of ageing, including cognitive ageing, frailty and multi-morbidity. Clinically she specialises in the management of acute delirium and dementia in medically complex patients.
The seminar will discuss how the study of epigenetic regulation and gene expression signatures in the gingival tissues can enhance our understanding of the pathobiology of periodontitis.
The seminar will describe differences in DNA methylation patterns and mRNA expression in gingival tissues in states of periodontal health, gingivitis and established periodontitis. An overview of published and ongoing studies will be presented, and the significance of the findings will be discussed.
Participants will familiarize themselves with the concepts of gene expression and epigenetic regulation in the gingival tissues, and the association of transcriptomic signatures with clinical periodontal phenotypes.
GDC Development Outcome C
Panos N. Papapanou, DDS, PhD is Professor of Dental Medicine, Director of the Division of Periodontics, and Chairman of the Section of Oral, Diagnostic and Rehabilitation Sciences, at the College of Dental Medicine, Columbia University, New York, USA. He has earned DDS degrees from the University of Athens, Greece, and Columbia University, NY, USA, a PhD from Göteborg University, Sweden, and has received post-doctoral training in Oral Microbiology at the Forsyth Institute, Boston, MA. His research has been funded by the National Institutes of Health, foundations and industry, and encompasses studies of the epidemiology of periodontal disease, the assessment of microbial and host-derived risk factors, the pathobiology of periodontitis and its role in general health. He is the recipient of several international awards, most recently the William Gies Award for Clinical Research from the International Association for Dental Research (2015), the Yngve Ericsson Prize in Prophylactic Dentistry Research jointly awarded by Swedish Patent Revenue Fund for Prophylactic Odontology and the European Organization for Caries Research (2016), and the Distinguished Scientist Award for Basic Research in Periodontal Disease from the International Association for Dental Research (2017). He is board member of several journals, Fellow of the American College of Dentists, and Past President and Councilor of the Periodontal Research Group of the IADR.
There is evidence of a relationship between periodontitis and rheumatoid arthritis. There has been an explosion of studies investigating the relationship between rheumatoid arthritis and the bacteria associated with periodontitis, and the host response in periodontal disease. This lecture will examine the evidence and in particular scrutinise whether periodontal disease, and periodontitis associated bacteria, might predispose to rheumatoid arthritis and whether successful periodontal treatment might improve both oral health and the symptoms of rheumatoid arthritis.
- Understand some of the proposed mechanism by which periodontal disease may impact on rheumatoid arthritis, and vice versa.
- Be aware of some of the evidence investigating the impact of periodontal treatment on rheumatoid arthritis.
GDC Development Outcome C
Shauna is an Honorary Consultant and Senior Clinical Lecturer in Periodontics at the University of Glasgow, where she is the Clinical Dental Research Facility Lead and Lead for Undergraduate teaching in Periodontics. During her undergraduate dental training in Glasgow, Shauna completed an intercalated degree in immunology, which extended to an intercalated PhD examining the role of cytokines in inflammation, funded by Arthritis Research UK. Shauna completed specialist training in Periodontics in 2011 and commenced an Honorary Consultant Post in Periodontics - at the same time becoming the first dentist to be awarded the Scottish Funding Council’s Senior Clinical Research Fellowship. The connections with arthritis research have continued with her research team investigation the immune response in the oral cavity and the relationship between periodontitis and arthritis.
To promote the wider recognition of periodontitis as a modifiable risk factor for Alzheimer’s disease at the World Dementia Council (https://worlddementiacouncil.org/), National Institutes of Health (NIH) and Alzheimer’s Research UK (ARUK) (www.alzheimersresearchuk.org/ARUK), and the Alzheimer’s disease Society (https://www.alzheimers.org.uk/) levels. The fact that periodontitis is modifiable means that the onset and progression of AD may be reduced by improving the oral/general health and life-styles.
1. To transfer knowledge at the research and professional interface
2. Better management of periodontal disease at individual patient level
3. To motivate the public in the importance of good oral hygiene
3: Dental professionals must reach out and treat periodontal disease in middle age (50 years age and over) particularly if they show anxiety
- A basic introduction to Alzheimer’s disease (AD) as an example of dementia
- The infection concept with aberrant infections and microbial habitants from hosts’ dysbiotic microbiomes
- The pathways leading from poor oral health to AD development and progression
- Interventions (in brief), which can reduce AD, through focusing on oral health
- Practical advice on how to translate research findings on the oral health-AD link to benefit patients.
GDC Development Outcome C
Drs Gillian Cole, Jim Neal, Geoff Newman & Prof Paul Morgan nurtured Sim’s interest in neurodegenerative diseases leading to a Ph.D at Cardiff University. Three postdoctoral positions (Profs. Wynford-Thomas, Rachel Waddington and Charlie Archer) later, Sim took up a Senior Research Fellow position at the University of Central Lancashire (UCLan) with Prof. StJohn Crean to develop links with oral health and dementia. Sim now leads the School of Dentistry and UCLan’s research in the infection model of Alzheimer’s disease (AD) with periodontitis and Sim’s ultimate goal is to discover causative links of periodontitis with the development of AD. Sim hopes that this research will help to improve oral/general health and even life-style behaviours and so delay or indeed take the first steps towards “prevent AD” campaign.
To present the possible career opportunities and outcome qualifications in Periodontology for Dentists, Hygienists and Therapists
Present formal and informal programs of training
Provide attendees with information and contacts to develop their interest in Periodontology Create a forum for discussion for postgraduate training in the field of Periodontology
Identification of formal and informal training opportunities in the field of Periodontology
GDC Development Outcomes B,C & D
Ian is a Specialist Periodontist based in Liverpool and Wilmslow. He is the former teaching lead in Periodontics and Senior Clinical Teacher in Periodontics at Liverpool University and lectures around the UK with Phil Ower and the PerioCourses team.
Modern medicine is doing a remarkable job in maintaining the relatively good health of an increasingly ageing population. One of the consequences of this is that a very large proportion of the population is taking one or more medications on a regular basis. It has long been recognised that some systemic drugs may influence the periodontal tissues, such as those causing gingival overgrowth. However these effects are increasingly common with the wide spread use of many medications, and the development of novel therapies for both chronic inflammatory conditions and treatment of malignancies.
To discuss the effects of prescription drugs on the periodontal tissues.
- To discuss the rise in use of many medicines for the management of common chronic non-communicable diseases;
- To discuss the effects of calcium channel blocker drugs on periodontal disease;
- To briefly consider other medications which can cause gingival overgrowth;
- To discuss whether statins may have effects on periodontal disease;
- To briefly review the effects of anti –rheumatoid therapies based on cytokine blocking on periodontal disease;
- To briefly review the effects of other drugs, including novel anti–cancer drugs, on periodontal disease.
At the end of the session the participant should be able to :
- To describe the most widely used classes of drugs today;
- To recognise the role of Calcium Channel Blocker drugs on the periodontal tissues;
GDC Development Outcome C
Francis Hughes is Professor of Periodontology at Kings College London. He completed his undergraduate training at Guys Hospital in 1979 and then carried out his postgraduate clinical and research training at the London Hospital Medical School and as a Postdoctoral Research Fellow at the University of Toronto, with Prof Tony Melcher. He was appointed Professor of Periodontology at Barts & The London in 1999, and took up his current position at KCL in 2009.
Francis is a past president of the British Society of Periodontology and of the Pan European Federation of IADR and was chair of the Europerio8 conference held in London in June 2015. He has served on the Editorial Boards of Journal of Dental Research, Journal of Clinical Periodontology, Oral Diseases and Journal of Periodontal Research and a co-author of the recent review of systemic conditions affecting the Periodontium for the 2017 World Workshop in Classification of Periodontal Diseases.
Francis’s research interests include systemic risk factors and biomarkers of periodontitis and the biological mechanisms of periodontal regeneration, bone formation and periodontal stem cell biology. He is an enthusiastic teacher and has written 2 undergraduate textbooks in periodontology – “Pathology of Periodontal Disease”, and “Clinical Problem Solving in Periodontology and Implant Dentistry.”
To explain the impact of common antiseptics on bacterial populations and how bacteria can adapt to biocidal stress. To outline the evidence suggesting risks of biocide-antibiotic cross resistance.
- To be aware of major types of antiseptics in use
- To understand the role of bacterial biofilms in antimicrobial resistance
- To be able to describe the potential mechanisms of biocide-antibiotic cross resistance
GDC Development Outcome C
My research group studies the molecular mechanisms of antimicrobial resistance with focus on understanding how, where, when and why bacteria evolve antibiotic resistance. I am particularly interested in bacterial biofilms and we are investigating how bacteria adapt to antimicrobial pressure within a biofilm. One of the focuses of the group is understanding how bacteria can adapt to biocide exposure and whether antibiotic cross-resistance can occur. We use a variety of contemporary molecular microbiology approaches to study bacterial survival and resistance mechanisms. My research career started at the University of Birmingham where I completed a PhD studying mechanisms of multidrug resistance in E. coli before postdoctoral work. I was then awarded a BBSRC David Phillips fellowship to start my own group studying the evolution of biocide-antibiotic cross resistance following which I became a tenured member of academic staff. I moved to the Quadram Institute in Norwich at the start of 2017. I have published over 70 articles relating to antimicrobial resistance since 2001.
1. To describe the composition of the oral microbiome
2. To compare the effect of antimicrobials on the oral and gut microbiomes
3. To compare and contrast the effect of modern oral hygiene procedures and diets on the composition of the oral microbiome and aspects of systemic health
1. Appreciate the complexity of the oral microbiome
2. Understand the effect of antimicrobials on the oral and gut microbiomes
3. State which dietary components affect the oral microbiome
GDC Development Outcome C
William Wade is Professor of Oral Microbiology at King's College London and Honorary Senior Research Investigator at the Forsyth Institute, Cambridge, USA. He qualified in Microbiology in 1978 at the University of East Anglia. He pursued a PhD in Oral Microbiology at Cardiff Dental School and was appointed to a Lectureship there in 1987. He then moved in 1993 to the University of Bristol to take up a Senior Lectureship in Oral Microbiology, and in 1996 was appointed Professor of Oral Microbiology at King's College London. In 2013 he took up a Chair in Oral Microbiology at Queen Mary University of London but returned to King's in 2018.
His current interests include the molecular characterisation of the oral microbiome in health and disease, the cultivation of previously uncultivated bacteria and the development and evaluation of antimicrobials and prebiotics and probiotics for the prevention and treatment of oral diseases.
The aim of dental treatment is the long-term retention of natural teeth in a healthy, functional, aesthetically acceptable, and painless state. Implants should come into play only if natural teeth are lost. Thus, tooth loss is the ultimate failure in dentistry and its prevention is the ultimate measure of success.
- What is the aim of dental treatment?
- How long do periodontally compromised and properly treated teeth last?
- How long do implants last if they have replaced missing teeth?
- What makes teeth and implants last longer?
GDC Development Outcomes A & C
1982-1987 Dental School at the University of Cologne
1988-1989 Captain of the Medical Staff in the German Air Force
1989 Dr. med. dent., 1989-1992 periodontal training at the Dept. of Periodontology of the University of Münster
1992 Fachzahnarzt für Parodontologie (Specialist for Periodontology)
1992-2004 Dept. of Conservative Dentistry at the University of Heidelberg, since 1995 Clinical Director, since 2000 Head of the Section of Periodontology
1997 Habilitation (PhD)
2003 Associate Professor (Heidelberg)
since 2004 Chair of the Dept. of Periodontology at the Centre of Center of Dentistry and Oral Medicine (Carolinum)
2012-2014 Managing Director of the Center of Dentistry and Oral Medicine (Carolinum)
2014-2015 temporary chair of the Dept. of Conservative Dentistry, Johann Wolfgang Goethe-University Frankfurt
2011-2016 President of the German Society of Periodontology (Deutschen Gesellschaft für Parodontologie [DG PARO])
on the Editorial Board of Journal of Clinical Periodontology.
Main fields of work: diagnosis and therapy of furcation involvement, computer-assisted radiographic diagnosis, regenerative periodontal therapy (GTR), local antibiotics, long-term results after periodontal therapy, interaction of periodontal and other diseases.
To discuss how to manage the expectations of patients and ensure you have their consent.
To demonstrate the importance of clear communication in managing the expectations of patients.
To explain recent changes in the laws surrounding consent.
To discuss how these changes have impacted the dental team.
Understand the importance of managing the expectations of patients.
Appreciate the requirements of obtaining the consent for treatment.
GDC Development Outcome A, B & D
Dr Briggs qualified in 1989 and has worked in the Community Dental Service as well as General Dental Practice.
He gained an MSc in Periodontology 1995 and is on the GDC specialist register for Periodontics. Since 1995 Dr Briggs has provided specialist periodontal treatment in both Salaried Dental Services and Private Practice.
Dr Briggs started working part time for the DDU in 2005.
From 2007 to 2009 he worked part time as a Clinical Tutor at the School for Professionals Complementary to Dentistry in Portsmouth.
From February 2009 Dr Briggs started working full time for the DDU and became Deputy Head of the DDU in 2016.